Safe chassis catalog
Every biosensor is built in one of these hosts. The catalog is restricted to non-pathogenic BSL-1 organisms; GRAS / probiotic status is shown where it applies.
Bacillus subtilis 168
Gram-positive, spore-forming model bacterium with QPS (EFSA) status and a long history of safe industrial use. Spores make it robust for field-deployable and environmental biosensors.
Corynebacterium glutamicum (ATCC 13032)
A GRAS industrial workhorse used for food-grade amino-acid production at megaton scale. Robust, stress-tolerant, and easy to grow at high density — well suited to industrial-process and chemical monitoring.
E. coli K-12 (MG1655)
The non-pathogenic laboratory workhorse. K-12 strains have lost the ability to colonize the human gut and are the reference BSL-1 host for genetic engineering, with the deepest tooling of any bacterial chassis.
E. coli Nissle 1917
A probiotic E. coli used in humans for over a century (Mutaflor). Colonizes the gut safely, making it the chassis of choice for clinical / gut biomarker biosensors.
Lactiplantibacillus plantarum (WCFS1)
A GRAS probiotic lactic acid bacterium that persists in the gut better than L. lactis. Robust to gut bile and acid, making it a strong chassis for ingestible clinical/gut biosensors and fermented-food monitoring.
Lactococcus lactis (MG1363)
Food-grade, GRAS lactic acid bacterium used for centuries in dairy fermentation. Non-colonizing and ideal for ingestible / clinical biosensors where a food-safe, gut-transient host is wanted.
Pseudomonas putida KT2440
A certified safety-strain soil bacterium with exceptional solvent/stress tolerance and diverse metabolism. The premier chassis for environmental biosensing of pollutants and heavy metals in soil and water.
Saccharomyces cerevisiae (BY4741)
GRAS baker's yeast — the model eukaryote. Being a eukaryote, it can host human nuclear receptors and GPCRs, unlocking sensing of steroids, hormones, and other eukaryotic-specific ligands that bacteria cannot detect. dCas9 CRISPRi/CRISPRa are well established.
Synechocystis sp. PCC 6803
A non-pathogenic photosynthetic cyanobacterium. It runs on light and CO2, so biosensors built in it are self-powered — ideal for long-term, deployable environmental and water-quality monitoring without added nutrients.